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The Origins of Genome Architecture by Michael Lynch

The Origins of Genome Architecture Michael Lynch ebook
Publisher: Sinauer Associates Inc
Page: 258
Format: pdf
ISBN: 0878934847, 9780878934843

This is consistent with some earlier empirical observations [84,85] and with the original hypothesis by Lynch and Conery [21], linking effective population size (Ne) to genome size and proposing a central role of non-adaptive processes in the evolution of genome architecture. In my mind, there is little question that drift plays a central role at the level of genome architecture (despite some of the nutty statements by the Encode crowd). One of the best books I have read in a long time. The biological role of TEs remains unclear, although they have profound mutagenic impact on eukaryotic genomes and the origin of repetitive families often correlates with speciation events. I think Darwin would have liked it. Well-written, clearly argued, well referenced and important. In another breakthrough, the sequencing of the sea sponge genome offers unprecedented insights in to the origin of the animal kingdom and how ancient genes contribute to human biology and health. Origins of the Phylum Amoebozoa but also provide a suitable outgroup for understanding of some of the special features of . Over Christmas I read Michael Lynch's new book “The Origins of Genome Architecture”. I'm now trying to understand the extent to which this might also be true at the level of protein architecture and cellular Maybe our work is more akin to paleontology, describing history and processes.